The shallow quake struck at 11:47 pm (18:02 GMT) on Friday around the western area of Jajarkot, a hilly district about 500 kilometers (310 miles) west of the capital, Kathmandu, that is home to about 190,000 people.
The US Geological Survey put the magnitude at 5.6 and said it was just 18 kilometers (11 miles) deep.
The tremors were felt as far away as Kathmandu and even about 600km (375 miles) away in the Indian capital New Delhi.
“The death toll has reached 119 and at least 100 have been injured,” Karnali Province police spokesman Gopal Chandra Bhattarai was quoted as saying by Al Jazeera.
MP/PR