Dina Ghorbani scored Iran’s solitary goal at the Dushanbe Central Stadium in Tajikistan.
Iran are scheduled to play Tajikistan on Thursday, while Uzbekistan meet Kyrgyzstan.
The Persians had been held by Kyrgyzstan 1-1 in their opening match.
The Central Asian Football Association (CAFA) is one of five regional bodies of governance in association football in Asia. It governs association football, futsal, and beach football in Central Asia.
CAFA consists of six national association members, namely Iran, Uzbekistan, Tajikistan, Kyrgyzstan, Afghanistan and Turkmenistan.
AMK/TT